KLK6 Antibody - N-terminal region

Artikelnummer: ASB-ARP33888_P050
Artikelname: KLK6 Antibody - N-terminal region
Artikelnummer: ASB-ARP33888_P050
Hersteller Artikelnummer: ARP33888_P050
Alternativnummer: ASB-ARP33888_P050-25UL,ASB-ARP33888_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Canine, Equine, Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6
Alternative Synonym: hK6, Bssp, Klk7, SP59, PRSS9, PRSS18
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 25kDa
NCBI: 5653
UniProt: Q92876
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Lung
WB Suggested Anti-KLK6 Antibody Titration: 0.2-1 ug/ml
Positive Control: 721_B cell lysate
Host: Rabbit
Target Name: KLK6
Sample Type: Jurkat Whole Cell lysates
Antibody Dilution: 1.0ug/ml
KLK6 antibody - N-terminal region (ARP33888_P050) in Human 721_B using Western Blot