Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6
Alternative Synonym:
AOVD2, MADH6, MADH7, HsT17432
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Heart
Human Lung
WB Suggested Anti-SMAD6 Antibody Titration: 0.5-1.0ug/ml Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that SMAD6 is expressed in Jurkat
SMAD6 antibody - N-terminal region (ARP32690_T100) in Human Jurkat using Western Blot
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