Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K7IP2
Alternative Synonym:
CHTD2, TAB-2, MAP3K7IP2
MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Spermatophore
Human Stomach
WB Suggested Anti-MAP3K7IP2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysateTAB2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
MAP3K7IP2 antibody - N-terminal region (ARP32402_P050) in Human HepG2 using Western Blot
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