Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1
Alternative Synonym:
AAS, FGDY, MRXS16, ZFYVE3
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
WB Suggested Anti-FGD1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Raji cell lysateFGD1 is supported by BioGPS gene expression data to be expressed in Raji
FGD1 antibody - C-terminal region (ARP31673_P050) in Human Raji using Western Blot
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