VTP50469, CAS [[2169916-18-9]]
Artikelnummer:
BYT-ORB1308940
Produktübersicht
Artikelname:
VTP50469, CAS [[2169916-18-9]]
Artikelnummer:
BYT-ORB1308940
Hersteller Artikelnummer:
orb1308940
Alternativnummer:
BYT-ORB1308940-1,BYT-ORB1308940-10,BYT-ORB1308940-100,BYT-ORB1308940-25,BYT-ORB1308940-5,BYT-ORB1308940-50
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, Menin-MLL, Menin-MLL interaction, leukemia, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor, differentiation, antiproliferative, Apoptosis, survival, protein-protein, VTP 50469, VTP50469, VTP-50469
Produktbeschreibung
VTP50469 is a potent, orally bioavailable small molecule that selectively inhibits the Menin-MLL interaction with sub-nanomolar affinity (Ki = 104 pM). It demonstrates robust anti-leukemic efficacy in both cellular assays and in vivo models, making it a valuable chemical probe for researching MLL-rearranged and NPM1-mutant leukemias.
Produkteigenschaften
Molekulargewicht:
630.82
Reinheit:
99.55% (May vary between batches)
CAS Nummer:
[2169916-18-9]
Formel:
C32H47FN6O4S
Target-Kategorie:
Epigenetic Reader Domain,Histone Methyltransferase,Apoptosis
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: DMSO:125 mg/mL (198.15 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.34 mM)
