SRY Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51535
Artikelname: SRY Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51535
Hersteller Artikelnummer: AP51535
Alternativnummer: ABT-AP51535-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human
Alternative Synonym: Sex-determining region Y protein, Testis-determining factor, SRY, TDF
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5-[AT]AACAA[AT]-3.
Klonalität: Polyclonal
NCBI: 6736
UniProt: Q05066