GAB2 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51222
Artikelname: GAB2 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51222
Hersteller Artikelnummer: AP51222
Alternativnummer: ABT-AP51222-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human
Alternative Synonym: GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp100, GAB2, KIAA0571
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Klonalität: Polyclonal
NCBI: 9846
UniProt: Q9UQC2