Caspase 10 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51038
Artikelname: Caspase 10 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51038
Hersteller Artikelnummer: AP51038
Alternativnummer: ABT-AP51038-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, ICC, IHC-P, WB
Spezies Reaktivität: Human, Mouse, Rat
Alternative Synonym: Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, Caspase-10 subunit p23/17, Caspase-10 subunit p12, CASP10, MCH4
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Klonalität: Polyclonal
NCBI: 843
UniProt: Q92851