BRMS1 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51021
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| Artikelname: | BRMS1 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51021 |
| Hersteller Artikelnummer: | AP51021 |
| Alternativnummer: | ABT-AP51021-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IHC-P, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Breast cancer metastasis-suppressor 1, BRMS1 |
| Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at Lys-310. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
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