Functional NS5B (HCV) Antibody, mAb (blocking), Clone: [5B-12B7], Monoclonal
Artikelnummer:
ABT-ADP0014-U0100
Hersteller Artikelnummer:
ADP0014-U0100
Alternativnummer:
ABT-ADP0014-U0100-100UG
Hersteller:
Abcepta
Kategorie:
Antikörper
Applikation:
ICC, IP
Alternative Synonym:
Nonstructural Protein 5B
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
Klonalität:
Monoclonal
Konzentration:
1mg/ml
Klon-Bezeichnung:
[5B-12B7]
Antibody Type:
Monoclonal Antibody
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
