Functional TRAIL-R1 (human) Antibody, mAb(preservative free), Clone: [HS101], Monoclonal
Artikelnummer:
ABT-ADP0012-U0100
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| Artikelname: | Functional TRAIL-R1 (human) Antibody, mAb(preservative free), Clone: [HS101], Monoclonal |
| Artikelnummer: | ABT-ADP0012-U0100 |
| Hersteller Artikelnummer: | ADP0012-U0100 |
| Alternativnummer: | ABT-ADP0012-U0100-100UG |
| Hersteller: | Abcepta |
| Kategorie: | Antikörper |
| Applikation: | FC, ICC, IP |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | TRAIL Receptor 1, DR4, APO2, TNFRSF10A, CD261 |
| TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa. |
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