Cynomolgus MAdCAM-1 Protein, His Tag, low endotoxin, Unconjugated, Human
Artikelnummer:
ABS-MAM-C52H3-100UG
Hersteller Artikelnummer:
MAM-C52H3-100ug
Alternativnummer:
ABS-MAM-C52H3-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Unconjugated
The mucosal addressin cell adhesion molecule1 (MAdCAM1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the alpha4beta7 integrin expressed on lymphocytes. - Proteine/Peptide
