Mouse MASP2 (287-685) Protein, His Tag, Unconjugated, E. coli
Artikelnummer:
ABS-MA2-M51H3-1MG
Hersteller Artikelnummer:
MA2-M51H3-1mg
Alternativnummer:
ABS-MA2-M51H3-1MG
Hersteller:
AcroBiosystems
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
Mannanbinding lectinassociated serine protease 2 (MASP2) is a member of the lectin pathway of complement and is one of two splice products from the MASP2 gene. The protein is secreted from the liver as a zymogenic protein consisting of 671 residues and circulates at a concentration of approximately 0.41 µg/mL in the serum. MASP2 is associated with patternrecognition molecules as a homodimer that is activated by MASP1 when bound to an activating surface resulting in an Achain and a Bchain linked by a disulphide bond. MASP2 is also capable of autoactivating. Activated MASP2 cleaves C2 and C4, which leads to formation of the C3 convertase, C4b2a, and activation of complement. - Proteine/Peptide
