Rhesus macaque IL-18 Protein, Tag Free (MALS & SPR verified), Unconjugated, E. coli
Artikelnummer:
ABS-IL8-R5113-100UG
Hersteller Artikelnummer:
IL8-R5113-100ug
Alternativnummer:
ABS-IL8-R5113-100UG
Hersteller:
AcroBiosystems
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Unconjugated
Interleukin18 (IL18) is a potent proinflammatory cytokine that induces interferongamma (IFNgamma) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL12. IL18 also functions in developmental regulation of Tlymphocyte helper type I cells and in Fasmediated cytotoxicity. Suppression of IL18 activity is being investigated for treatment of chronic inflammatory diseases such as Crohns disease and rheumatoid arthritis. It acts by inducing heterodimerization of the two subunits of its receptor, IL18RAlpha and IL18RBeta shows structural similarity to IL1. - Proteine/Peptide
