Biotinylated Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Complex Protein (Monomer, MALS verified)
Artikelnummer:
ABS-HLE-H82E8-25UG
Hersteller Artikelnummer:
HLE-H82E8-25ug
Alternativnummer:
ABS-HLE-H82E8-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. The PRAME (SLLQHLIGL) was shown to be recognized by HLAA*0201 tumorinfiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCRT studies. The Human HLAA*0201 PRAME (SLLQHLIGL) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M and PRAME (SLLQHLIGL) peptide. - Proteine/Peptide
