Monoclonal Antibody to Arginase-1 (Clone: ABM4B35)
Artikelnummer:
ABI-10-7543-25
- Bilder (3)
| Artikelname: | Monoclonal Antibody to Arginase-1 (Clone: ABM4B35) |
| Artikelnummer: | ABI-10-7543-25 |
| Hersteller Artikelnummer: | 10-7543-25 |
| Alternativnummer: | ABI-10-7543-25-25UG |
| Hersteller: | Abeomics |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | A partial length recombinant Arginase-1 protein (amino acids 11-230) was used as the immunogen for this antibody |
| Alternative Synonym: | ARG1 |
| Arginase-1 (Arg-1) is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of arginine to ornithine and urea. It is expressed in normal human liver with a high degree of specificity, concentrated in periportal hepatocytes. Arginase-1 are urea cycle enzymes used to distinguish hepatocellular carcinoma from other carcinomas. Two transcript variants encoding different isoforms have been found for this gene. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. |
| Application Verdünnung: | Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5-15 µg/ml |
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Fig-1: Immunohistochemical analysis of Arginase-1 in human liver tissue using Arginase-1 antibody (Clone: ABM4B35) at 15 µg/ml. |
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Fig-2 : Immunohistochemical analysis of Arginase-1 in human liver tissue using Arginase-1 antibody (Clone: ABM4B35) at 5 µg/ml. |
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Fig-3 : Western blot analysis of Arginase-1. Anti- Arginase-1 antibody (Clone: ABM4B35) was tested at 2 µg/ml on human liver lysate. |
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