Human spleen membranes from a patient with hairy cell leukemia was used as immunogen to generate the CD31 (PECAM-1) antibody.
Alternative Synonym:
PECAM1
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules, and plays key roles in leukocyte migration, angiogenesis, and integrin activation. CD31 is expressed on endothelial and hematopoeitic (platelets, monocytes, macrophages, granulocytes, T and B lymphocytes, dendritic, bone marrow stem and adult) cells.
Fig.1: FLOW Cytometry analysis of CD31 in human PBMC using 0.5µg antibody per 10 6 cells. Green represents isotope control. Red represents anti-CD31 antibody (Clone: ABM3E63). Goat anti-mouse IgG conjugated with PE was used as secondary antibody.
Fig: 3 Immunohistochemical analysis of CD31 in human Lung tissue using CD31 antibody (Clone: ABM3E63) at 10 µg/ml.
Fig: 2 Immunohistochemical analysis of CD31 in human lung squamous cell carcinoma (left) and bladder transitional cell carcinoma (right) using CD31 antibody (Clone: ABM3E63) at 1: 200 dilution.
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