A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.
Alternative Synonym:
CLEC6A||CLECSF10||DECTIN2
Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10 6 cells, Immunohistochemical analysis: 5 µg/ml
Fig-1: Western blot analysis of Dectin 2 Anti- Dectin 2 antibody (Clone: ABM2H28) was used at 2 µg/ml on Raw lysate.
Fig-2 : Immunohistochemical analysis of Dectin-2 in Renal Cell Carcinoma using Dectin-2 antibody (Clone: ABM2H28) at 5 µg/ml.
Fig-3: Intracellular flow analysis of Dectin-2 in human PBMC (Lymphocytes) using 0.5 µg/10 6 cells of Dectin-2 antibody (Clone: ABM2H28). Green represents isotype control, red represents anti-Dectin-2 antibody. Goat anti-mouse PE conjugate was used as secondary.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
