What is ifinatamab biosimilar research grade? Ifinatamab is a humanized IgG1-kappa monoclonal antibody against the human B7-H3 (CD276) protein, a type I transmembrane protein belonging to the B7 family which includes immune checkpoint molecules CTLA-4 and PD-L1. B7-H3 is highly expressed in various types of solid tumors with low expression in normal (healthy) tissues. It was reported that B7-H3 overexpression is associated with poor prognosis in several types of cancers. Ifinatamab biosimilar uses the same protein sequences as the therapeutic antibody ifinatamab.
In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Anwendungsbeschreibung:
Applications: ELISA,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways. ResearchArea: Cancer immunology. Shipping: Ice Bag
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