SFPQ Antibody - N-terminal region

Catalog Number: ASB-ARP40572_T100
Article Name: SFPQ Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP40572_T100
Supplier Catalog Number: ARP40572_T100
Alternative Catalog Number: ASB-ARP40572_T100-25UL,ASB-ARP40572_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFPQ
Alternative Names: PSF, POMP100, PPP1R140
SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5-CTGAGTC-3 in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 78kDa
NCBI: 6421
UniProt: P23246
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-SFPQ Antibody
Catalog Number: ARP40572
Paraffin Embedded Tissue: Human Intestine
Cellular Data: Epithelial cells of intestinal villas
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Rabbit Anti-SFPQ Antibody
Catalog Number: ARP40572
Paraffin Embedded Tissue: Human Skin
Cellular Data: Squamous epithelial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Rabbit Anti-SFPQ antibody
Catalog Number: ARP40572
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-SFPQ Antibody Titration: 1.25ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate.SFPQ is strongly supported by BioGPS gene expression data to be expressed in HepG2
Lanes:
Lane 1: 50ug Hela Lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:10,000
Gene Name:
SFPQ
Submitted by:
Archa Fox, University of Western Australia
SFPQ is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
SFPQ antibody - N-terminal region (ARP40572_T100) in Human HepG2 using Western Blot