INSIG1 Antibody - middle region
Catalog Number:
ASB-ARP40166_P050
- Images (6)
| Article Name: | INSIG1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP40166_P050 |
| Supplier Catalog Number: | ARP40166_P050 |
| Alternative Catalog Number: | ASB-ARP40166_P050-25UL,ASB-ARP40166_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human INSIG1 |
| Alternative Names: | INSIG-2 |
| Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Host: Rabbit Target Name: INSIG1 Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 3ug/ml |
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Host: Rabbit Target Name: INSIG1 Sample Tissue: Human OVCAR-3 Whole Cell Antibody Dilution: 2ug/ml |
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WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human Muscle |
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Host: Rabbit Target Name: WT1 Sample Type: 721_B Antibody Dilution: 1.0ug/mlINSIG2 is supported by BioGPS gene expression data to be expressed in 721_B |
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Host: Rabbit Target: INSIG2 Positive control (+): Human stomach (ST) Negative control (-): MCF7 (N10) Antibody concentration: 1ug/ml |
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INSIG1 Antibody - middle region (ARP40166_P050) in Human HT1080 Whole Cell using Western Blot |
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