CrkII Antibody, Mouse, Monoclonal
Catalog Number:
ABT-AP52769
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| Article Name: | CrkII Antibody, Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AP52769 |
| Supplier Catalog Number: | AP52769 |
| Alternative Catalog Number: | ABT-AP52769-100UL |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Alternative Names: | Adapter molecule crk,Avian sarcoma virus CT10 (v crk) oncogene homolog,CRK,CRK isoform 2,CRK isoform II,CRK_HUMAN,CRKII,FLJ38130,OTTHUMP00000115366,OTTHUMP00000198330,p38, Proto oncogene C crk,Proto-oncogene C-crk,v crk avian sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog (avian). |
| The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. |
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