MGC22487,Oct 3,Oct 4,Oct-3,Oct-4,OCT3,Oct4,Octamer binding protein 3,Octamer binding protein 4,Octamer binding transcription factor 3,Octamer-binding protein 3,Octamer-binding protein 4,Octamer-binding transcription factor 3,OTF 3,OTF 4,OTF-3,OTF3,OTF4, PO5F1_HUMAN,POU class 5 homeobox 1,POU domain class 5 transcription factor 1,POU domain transcription factor OCT4,POU domain, class 5, transcription factor 1,POU5F1.
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.