GRB2-associated-binding protein 2 (Phospho-Ser159) Antibody, Rabbit, Polyclonal
Biozol Catalog Number:
ABT-AP52551
Supplier Catalog Number:
AP52551
Alternative Catalog Number:
ABT-AP52551-100UL
Manufacturer:
Abcepta
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Alternative Names:
GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp100, GAB2, KIAA0571
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.