OCT2 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP52001
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| Article Name: | OCT2 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP52001 |
| Supplier Catalog Number: | AP52001 |
| Alternative Catalog Number: | ABT-AP52001-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2, OCT2 |
| Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. |
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