MLF1 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51795
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| Article Name: | MLF1 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51795 |
| Supplier Catalog Number: | AP51795 |
| Alternative Catalog Number: | ABT-AP51795-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1 |
| Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. |
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