XRCC4 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51697
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| Article Name: | XRCC4 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51697 |
| Supplier Catalog Number: | AP51697 |
| Alternative Catalog Number: | ABT-AP51697-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse |
| Alternative Names: | DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4 |
| Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. |
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