Von Hippel Lindau Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51677
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| Article Name: | Von Hippel Lindau Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51677 |
| Supplier Catalog Number: | AP51677 |
| Alternative Catalog Number: | ABT-AP51677-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Rat |
| Alternative Names: | Von Hippel-Lindau disease tumor suppressor, Protein G7, pVHL, VHL |
| Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. |
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