STAM2 (pY192) Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51654
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| Article Name: | STAM2 (pY192) Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51654 |
| Supplier Catalog Number: | AP51654 |
| Alternative Catalog Number: | ABT-AP51654-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP |
| Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
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