GLUR4 (pS862) Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51646
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| Article Name: | GLUR4 (pS862) Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51646 |
| Supplier Catalog Number: | AP51646 |
| Alternative Catalog Number: | ABT-AP51646-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Glutamate receptor 4, GluR-4, GluR4, AMPA-selective glutamate receptor 4, GluR-D, Glutamate receptor ionotropic, AMPA 4, GluA4, GRIA4, GLUR4 |
| Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
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