CD120a Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51573
Article Name: CD120a Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51573
Supplier Catalog Number: AP51573
Alternative Catalog Number: ABT-AP51573-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC-P, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tumor necrosis factor receptor superfamily member 1A, membrane form, Tumor necrosis factor-binding protein 1, TBPI, TNFRSF1A, TNFAR, TNFR1
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Clonality: Polyclonal
NCBI: 7132
UniProt: P19438