EIF2AK1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP42405_P050
- Bilder (6)
| Artikelname: | EIF2AK1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP42405_P050 |
| Hersteller Artikelnummer: | ARP42405_P050 |
| Alternativnummer: | ASB-ARP42405_P050-25UL,ASB-ARP42405_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2AK1 |
| Alternative Synonym: | HCR, HRI, hHRI, LEMSPAD |
| EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3 end slightly overlaps the 3 end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme. Sequence Note: The sequence AF181071.1 is a chimeric mRNA clone. Only the heme-regulated initiation factor 2-alpha kinase region was propagated into this RefSeq record. |
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25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Two isoforms at 71 kDa contain the peptide sequence and the protein is phosphorylated. |
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WB Suggested Anti-EIF2AK1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Lung |
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Host: Rabbit Target Name: EIF2AK1 Sample Type: Human Hela Antibody Dilution: 1.0ug/mlEIF2AK1 is strongly supported by BioGPS gene expression data to be expressed in HeLa |
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Host: Rabbit Target Name: EIF2AK1 Sample Type: Human 293T Antibody Dilution: 1.0ug/mlEIF2AK1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells |
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Host: Rabbit Target: EIF2AK1 Positive control (+): Hela (HL) Negative control (-): Human brain (BR) Antibody concentration: 1ug/ml |
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EIF2AK1 antibody - N-terminal region (ARP42405_P050) in Human Lung using Western Blot |
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