BAG2 Antibody - C-terminal region
Artikelnummer:
ASB-ARP42177_T100
- Bilder (6)
| Artikelname: | BAG2 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP42177_T100 |
| Hersteller Artikelnummer: | ARP42177_T100 |
| Alternativnummer: | ASB-ARP42177_T100-25UL,ASB-ARP42177_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2 |
| Alternative Synonym: | BAG-2, dJ417I1.2 |
| BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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Rabbit Anti-BAG2 Antibody Catalog Number: ARP42177 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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WB Suggested Anti-BAG2 Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysateBAG2 is supported by BioGPS gene expression data to be expressed in Jurkat |
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Sample Type: Lane 1: 20ug untransfected human Saos2 cells Lane 2: 20ug siRUVBL transfected human Saos2 cells Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:3000 Color/Signal Descriptions: BAG2 Gene Name: Wenwei Hu, Xuetian Yue, Rutgers Cancer Institute of New Jersey. Submitted by: |
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Host: Rabbit Target Name: BAG2 Sample Tissue: Human HepG2 Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target: BAG2 Positive control (+): HepG2 (HG) Negative control (-): Human liver (LI) Antibody concentration: 5ug/ml |
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