The immunogen is a synthetic peptide directed towards the C terminal region of human CES2
Alternative Synonym:
iCE, CE-2, PCE-2, CES2A1
Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
WB Suggested Anti-CES2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysateCES2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells