DR5 Antibody, Mouse, Monoclonal
Artikelnummer:
ABT-AP52788
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| Artikelname: | DR5 Antibody, Mouse, Monoclonal |
| Artikelnummer: | ABT-AP52788 |
| Hersteller Artikelnummer: | AP52788 |
| Alternativnummer: | ABT-AP52788-100UL |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Fas like protein ,Apoptosis inducing protein TRICK2A/2B ,Apoptosis inducing receptor TRAIL R2 ,CD 262 ,CD262 ,CD262 antigen ,Cytotoxic TRAIL receptor 2 ,Death domain containing receptor for TRAIL/Apo 2L ,Death domain containing receptor for TRAIL/Apo2L ,Death receptor 5 ,DR 5 ,DR5 ,Fas like protein precursor ,KILLER ,KILLER/DR5 ,OTTHUMP00000123492 ,OTTHUMP00000123493 ,p53 regulated DNA damage inducible cell death receptor (killer) ,p53 regulated DNA damage inducible cell death receptor(killer) ,TNF related apoptosis inducing ligand receptor 2 ,TNF related apoptosis inducing ligand receptor 2 ,TNF-related apoptosis-inducing ligand receptor 2 ,TNFRSF10B ,TR10B_HUMAN ,TRAIL R2 ,TRAIL receptor 2 ,TRAIL-R2 ,TRAILR2 ,TRANCER ,TRICK2 ,TRICK2A ,TRICK2B ,TRICKB ,Tumor necrosis factor receptor like protein ZTNFR9 ,Tumor necrosis factor receptor like protein ZTNFR9 ,Tumor necrosis factor receptor superfamily member 10b ,Tumor necrosis factor receptor superfamily, member 10b ,ZTNFR9 |
| Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis. |
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