FAS (C-terminus) Antibody, Mouse, Monoclonal
Artikelnummer:
ABT-AP52701
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| Artikelname: | FAS (C-terminus) Antibody, Mouse, Monoclonal |
| Artikelnummer: | ABT-AP52701 |
| Hersteller Artikelnummer: | AP52701 |
| Alternativnummer: | ABT-AP52701-100UL |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | ALPS 1A,ALPS1A,APO 1,Apo 1 antigen,APO 1 cell surface antigen,Apo-1 antigen,APO1,Apo1 antigen,APO1 cell surface antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,APT 1,APT1,CD 95,CD 95 antigen, CD95,CD95 antigen,Delta Fas,Delta Fas/APO 1/CD95,Delta Fas/APO1/CD95,Fas (TNF receptor superfamily, member 6),FAS 1,FAS 827dupA,Fas AMA,FAS,FAS Antigen,Fas cell surface death receptor,FAS1,FASLG receptor,FASTM,sFAS,Surface antigen APO1,TNF receptor superfamily, member 6,TNFRSF 6,TNFRSF6,TNR6_HUMAN,Tumor necrosis factor receptor superfamily member 6. |
| Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). |
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