Antigen identified by monoclonal,BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,CD54 antigen, Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1, ICAM1_HUMAN,Intercellular adhesion molecule 1,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10, P3.58,Surface antigen of activated B cells,Surface antigen of activated B cells, BB2.
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.