GR (Phospho-Ser203) Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP52488
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| Artikelname: | GR (Phospho-Ser203) Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP52488 |
| Hersteller Artikelnummer: | AP52488 |
| Alternativnummer: | ABT-AP52488-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Mouse |
| Alternative Synonym: | Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL |
| Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. |
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