NOX4 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP52013
- Bilder (0)
| Artikelname: | NOX4 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP52013 |
| Hersteller Artikelnummer: | AP52013 |
| Alternativnummer: | ABT-AP52013-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | NADPH oxidase 4, 163-, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, NOX4, RENOX |
| Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity. |
Produktgarantie und fachkundiger Support
