MLF1 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51795
Artikelname: MLF1 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51795
Hersteller Artikelnummer: AP51795
Alternativnummer: ABT-AP51795-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Alternative Synonym: Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Klonalität: Polyclonal
NCBI: 4291
UniProt: P58340