DHRS2 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51756
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| Artikelname: | DHRS2 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51756 |
| Hersteller Artikelnummer: | AP51756 |
| Alternativnummer: | ABT-AP51756-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Dehydrogenase/reductase SDR family member 2, mitochondrial, 111-, Dicarbonyl reductase HEP27, Protein D, DHRS2 |
| Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. |
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