TFE3 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51672
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| Artikelname: | TFE3 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51672 |
| Hersteller Artikelnummer: | AP51672 |
| Alternativnummer: | ABT-AP51672-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, ICC, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Transcription factor E3, Class E basic helix-loop-helix protein 33, bHLHe33, TFE3, BHLHE33 |
| Transcription factor that specifically recognizes and binds E-box sequences (5-CANNTG-3). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
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