STAM2 (pY192) Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51654
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| Artikelname: | STAM2 (pY192) Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51654 |
| Hersteller Artikelnummer: | AP51654 |
| Alternativnummer: | ABT-AP51654-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP |
| Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
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