TIN2 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51566
Artikelname: TIN2 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51566
Hersteller Artikelnummer: AP51566
Alternativnummer: ABT-AP51566-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-P, WB
Spezies Reaktivität: Human
Alternative Synonym: TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2, TINF2, TIN2
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Klonalität: Polyclonal
NCBI: 26277
UniProt: Q9BSI4